Table 2.
The effect of placebo or salsalate on metabolic characteristics and inflammatory markers
| Characteristic | Placebo (n=18) |
Salsalate (n=22) |
||
|---|---|---|---|---|
| Baseline | Follow-up | Baseline | Follow-up | |
| Body weight (kg) | 103 (89, 118) | 103 (89, 117) | 109 (93, 114) | 109 (93, 114) |
| NEFA (μmol/l) | 385 (320, 430) | 390 (320, 440) | 345 (295, 500) | 435 (385, 500) |
| Adiponectin (mg/l) | 4.3 (3.7, 5.7) | 3.5 (2.8, 5.1)a | 5.2 (4.0, 7.5) | 5.2 (3.2, 6.9) |
| hsCRP (ng/l) | 55 (33, 120) | 60 (20, 108) | 63 (16, 89) | 39 (12, 69)a |
| MCP-1 (ng/l) | 118 (99, 152) | 119 (110, 132) | 109 (92, 165) | 109 (80, 141) |
Data are medians (25th, 75th percentile)
a
p<0.05 (Wilcoxon’s signed ranks test)
hsCRP, high sensitivity C-reactive protein; MCP-1, monocyte chemoattracting protein 1