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. 2010 Sep;161(2):393–404. doi: 10.1111/j.1476-5381.2010.00881.x

Figure 3.

Figure 3

Effect of CYP2C19 inhibitors on clopidogrel biotransformation. Clopidogrel (40 or 5 µM) was co-incubated with different concentrations of CYP2C19 inhibitors in the presence of human liver microsomes (HLM). Data are expressed as the percentage clopidogrel biotransformation in the presence of the inhibitor compared with biotransformation without inhibitor (100%). Data points consist of three individual determinations. Data are presented as mean ± SEM. **P < 0.001 versus control incubations.