Table 3.
Results between groups based on existence of detectable plasma neutrophil gelatinase-associated lipocalin (NGAL).
Study variable | Detectable NGAL (n = 23) | No detectable NGAL (n = 11) | P value |
---|---|---|---|
Laboratory | |||
Creatinine (μmol/L)—at rest | 84.0 ± 25.2 | 75.1 ± 17.5 | .24 |
Creatinine (μmol/L)—with stress | 87.4 ± 26.0 | 75.9 ± 19.4 | .16 |
ΔCreatinine (μmol/L) | 3.3 ± 8.1 | 0.8 ± 6.1 | .32 |
BNP (pg/mL)—at rest | 73.8 ± 57.6 | 53.9 ± 46.7 | .29 |
BNP (pg/mL)—with stress | 84.0 ± 64.3 | 57.5 ± 44.0 | .17 |
ΔBNP (pg/mL) | 10.2 ± 11.9 | 3.5 ± 4.8 | .03 |
cTnI (μg/L)—at rest | 0.010 ± 0.009 | 0.006 ± 0.003 | .05 |
cTnI (μg/L)—with stress | 0.013 ± 0.010 | 0.012 ± 0.016 | .86 |
ΔcTnI (μg/L) | 0.003 ± 0.007 | 0.007 ± 0.015 | .39 |
NT-proBNP (pg/mL)—at rest | 511.0 ± 642.0 | 303.1 ± 258.0 | .19 |
NT-proBNP (pg/mL)—with stress | 556.3 ± 685.6 | 312.1 ± 226.5 | .13 |
ΔNT-proBNP (pg/mL) | 45.4 ± 83.2 | 9.0 ± 46.0 | .11 |
AOPP (μmol/L)—at rest | 105.7 ± 102.0 | 89.3 ± 52.8 | .54 |
AOPP (μmol/L)—with stress | 85.8 ± 91.1 | 71.1 ± 24.7 | .48 |
ΔAOPP (μmol/L) | −19.9 ± 41.9 | −18.2 ± 38.6 | .91 |
Cardiovascular parameters | |||
Segmental perfusion defects—at rest | 3.8 ± 5.3 | 0.9 ± 2.1 | .03 |
Segmental perfusion defects—with stress | 8.2 ± 8.0 | 4.2 ± 3.7 | .06 |
ΔSegmental perfusion defects | 4.1 ± 3.8 | 3.3 ± 3.3 | .51 |
End diastolic volume (mL)—at rest | 108.4 ± 25.9 | 90.8 ± 31.7 | .14 |
End diastolic volume (mL)—with stress | 112.8 ± 32.5 | 90.2 ± 27.9 | .05 |
ΔEnd diastolic volume (mL) | 4.8 ± 11.2 | 0.8 ± 8.0 | .25 |
End systolic volume (mL)—at rest | 49.9 ± 21.5 | 34.7 ± 20.1 | .07 |
End systolic volume (mL)—with stress | 53.5 ± 27.5 | 34.4 ± 18.0 | .02 |
ΔEnd systolic volume (mL) | 3.6 ± 9.4 | 1.1 ± 7.4 | .44 |
Ejection fraction (%)—at rest | 55.8 ± 10.6 | 65.0 ± 10.7 | .03 |
Ejection fraction (%)—with stress | 55.1 ± 11.0 | 63.8 ± 10.3 | .04 |
ΔEjection fraction (%) | −0.7 ± 5.1 | −1.2 ± 4.9 | .78 |
Δ: delta (change from prestress to poststress test).
BNP: B-type natriuretic peptide, cTnI: cardiac troponin I, NT-proBNP: N-terminal-pro-B-type natriuretic peptide, AOPP: advanced oxidation protein products, NGAL: neutrophil gelatinase-associated lipocalin.