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Peak TNFR1 mRNA values were higher in responder patients than nonresponder patients. TNFR1 mRNA levels of genotype 1 HCV+ patients PBMC's were ascertained by real time PCR. Twelve responders, 25 NR/Rel and 12 responders, 24 NR/Rel were assessed for TNFR1 and TNFR2 mRNA levels, respectively (Panel A and B). Line indicates 2 SD above mean control levels. Levels did not vary between sample triplicates. Statistical differences were assessed by T test.
