(b)

	week 0	week 4–12	14–24	25–48
Patient 1	1.53	4.73
Patient 2	0.67		1.14
Patient 3	2.73		0.17
Patient 4	2.61			0.98
Patient 5	2.97		6.54
Patient 6	0.64	4.07		0.16
Patient 7			1.25	2.71
Patient 8	2.83		1.20	0.34
Patient 9	0.26		0.10	0.11
Patient 10			0.73	0.15
Patient 11			0.08	0.05
Patient 12			0.46	0.14