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. 2010 Nov 22;207(12):2663–2673. doi: 10.1084/jem.20100921

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© 2010 Babic et al.

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Figure 4. — m04 antagonizes the function of m152 in the downmodulation of H-2D^k. (A) Ly49A NFAT-GFP reporter cells were co-cultured with CBA/J MEFs that were infected with indicated viruses or left uninfected, and GFP expression was assessed (shaded histograms, infected; open histograms, uninfected). Data are representative of three independent experiments. (B) CBA/J MEFs were infected with indicated viruses or uninfected. Cells were harvested at the indicated time points (hpi, hours post infection) and stained for H-2D^k expression (shaded histograms). Irrelevant isotype matched antibody was used as a control (open histogram). Shaded box represents the time window of cocultivation of target cells with reporter cells (experiment shown in A). Data are representative of three independent experiments.