Figure 6.
Control of Δm04 MCMV is partially mediated via NKG2D. The indicated strains of mice were i.v. injected with 2 × 105 PFU of WT or Δm04 MCMV and 3 dpi viral loads in spleen were assessed. Mice were either untreated or NKG2D blockade was performed 6 h before infection by applying 300 µg of anti-NKG2D mAb. P values, unpaired two-tailed Mann-Whitney test. A circle depicts the titer for each individual mouse; the horizontal line indicates the mean. Data are representative of two independent experiments with five mice per group.