Table I.
Clinical characteristics of the cohort used in the gene expression analysis.
Pre-eclampsia (n = 13) | FGRa (n = 9) | Pre-eclampsia with FGR (n = 24) | Controls (n = 58) | |
---|---|---|---|---|
Maternal age (years) | 30 ± 5* | 34 ± 4 | 31 ± 5 | 31 ± 5 |
Gestational age (weeks) | 35 ± 3** | 32 ± 5** | 30 ± 4** | 39 ± 1 |
Systolic blood pressure (mmHg) | 153 ± 18** | 128 ± 15 | 151 ± 16** | 116 ± 11 |
Diastolic blood pressure (mmHg) | 95 ± 9** | 74 ± 8 | 97 ± 12* | 70 ± 9 |
Birthweight (g) | 2364 ± 510** | 1225 ± 21** | 1118 ± 470** | 3619 ± 469 |
Data are presented as mean ± SD. All case groups were compared with controls and P-values were computed based on t-test statistics.
a≤2 SD of expected weight, confirmed by at least one of the following: reduced fundal height in serial measurements, serial ultrasound biometry identifying failure to grow along a consistent centile or abnormal umbilical artery wave form.
*P < 0.05; **P < 0.001.