Table 2.
Characteristics of subjects included in breath sampling
| Healthy controls | CF - Ps. aeruginosa colonised | CF - Ps. aeruginosa non-colonised | |
|---|---|---|---|
| Number (n) | 17 | 16 | 13 |
| Age years (mean range) | 38 (25-54) | 26.9 (13-59) | 14.9 (6-43) |
| Male (%) | 38% | 63% | 53% |
| BMI (kg/m2) (mean range) | 19.07 (17.1-24.4) | 19.9 (14.8-37.2) | |
| Respiratory function: FEV1% | 44.92 (13-93) | 77.15 (48-99) | |
| FVC% | 59.51 (1.14-102) | 91.1 (55-120) | |
| Genetic analysis | Sweat test (3) | Sweat test (3) | |
| ΔF508/ΔF508 (9) | ΔF508/ΔF508 (5) | ||
| ΔF508/G542X (3) | ΔF508/G542X (1) | ||
| ΔF508/c.1339delA (1) | c.F508/c.1766+1g (1) | ||
| ΔF508/3849+10kbct (1) | |||
| c.1624g > t(p.g542x)/c.1 | |||
| 624g > t(p.g542x) (1) | |||
| ΔF508/P67L (1) | |||
| Diagnoses^ | |||
| Pancreatic insufficiency | 15 | 12 | |
| Chronic rhinosinuitis | 9 | 0 | |
| Osteopenia | 8 | 0 | |
| Gastro-oesophageal disease | 7 | 0 | |
| CF related diabetes | 4 | 3 | |
| Vitamin A, D & E deficiency | 5 | 1 | |
| Asthma | 5 | 0 | |
| Allergic bronchopulmonary | 0 | 3 | |
| aspergillosis | |||
| Distal intestinal obstruction | 1 | 2 | |
| syndrome | |||
| Previous tuberculosis | 1 | 0 | |
| Pancreatitis | 1 | 0 | |
| Chronic nasal polyps | 0 | 1 | |
| Haemoptysis | 0 | 0 | |
| Chronic eczema & ichthyosis | 1 | 1 |
^Some CF subjects had multiple diagnoses