Table 1.

The distribution and similarity^a of mycobacterial rhomboids

	Orthologs of Rv0110 (rhomboid protease 1)
			Query: Rv0110		Query: Rv1337
Species/strain	Rhomboid	Length	%Identity	E-value	%Identity	E-value
bH37Rv	Rv0110	284	100	5e-143	26	3e-06
cBCG Tokyo	JTY_0114	284	100	3e-143	26	3e-06
M. bovis	Mb0114	284	100	3e-143	26	3e-06
M.ulcerans†	MUL_4822	254	78	5e-104	27	1e-04
M. marinum	MMAR_0300	289	77	1e-103	26	2e-06
dM.sp. JLS	Mjls_5529	289	67	7e-97	NS	5e-06
eM.sp. Kms	Mkms_5237	289	66	2e-96	NS	3e-06
M. smegmatis	MSMEG_5036	250	64	8e-90	NS	7e-09
M. vanbaalenii	Mvan_5753	290	61	6e-77	NS	6e-08
M. gilvum	Mflv_1071	279	61	7e-73	NS	2e-06
M. abscessus	MAB_0026	287	38	7e-38	NS	1e-04
	Orthologs of Rv1337 (rhomboid protease 2)
H37Rv	Rv1337	240	27	7e-06	100	7e-137
BCG Tokyo	JTY_1373	240	27	7e-06	100	7e-137
M. bovis	Mb1372	240	27	7e-06	100	7e-137
M. marinum	MMAR_4059	222	26	8e-07	83	2e-106
M. avium†	MAV_1554	223	28	9e-05	75	7e-95
M. leprae†	ML1171	238	27	1e-04	73	7e-94
fMAP†	MAP2425c	223	NS	1e-04	74	6e-91
M. smegmatis	MSMEG_4904	219	NS	1e-05	73	9e-89
M.sp. JLS	Mjls_3833	229	26	1e-04	67	7e-81
M.sp. Kms	Mkms_3921	229	26	1e-04	67	7e-81
M. vanbaalenii	Mvan_4290	225	NS	4e-05	67	9e-77
M. gilvum	Mflv_2355	225	27	7e-04	66	9e-68
M. abscessus	MAB_1481	225	NS	8e-05	61	4e-67

^a: In comparison to Rv0110 and Rv1337 of M. tuberculosis H37Rv; lengths refer to number of amino acids

^b: Mycobacterium tuberculosis

^c: Mycobacterium bovis

^d: Mycobacterium species Jls

^e: Mycobacterium species Kms

^f: Mycobacterium avium subspecies Paratuberculosis

^†: Species with one rhomboid

NS: Not Significant (< 10% identity).