Table 2.
The distribution of structural topology on 40 transmembrane proteins that are extracted from release 15.0 of UniProt.
| UniProt ID | Sequence length | Protein name | Number of TM segment | Percentage of sequence length in specific structural topology | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| L | N | E | C | TM | S | Unknown | ||||
| O08984 | 620 | Lamin-B receptor | TM = 8 | 0.0% | 34.4% | 0.0% | 0.0% | 27.4% | 0.0% | 38.2% |
| O14786 | 923 | Neuropilin-1 | TM = 1 | 0.0% | 0.0% | 90.5% | 4.8% | 2.5% | 2.3% | 0.0% |
| O15431 | 190 | High affinity copper uptake protein 1 | TM = 3 | 0.0% | 0.0% | 33.7% | 33.2% | 33.2% | 0.0% | 0.0% |
| P01375 | 233 | Tumor necrosis factor | TM = 1 | 0.0% | 0.0% | 76% | 15% | 9% | 0.0% | 0.0% |
| P01589 | 272 | Interleukin-2 receptor alpha chain | TM = 1 | 0.0% | 0.0% | 80.5% | 4.8% | 7% | 7.7% | 0.0% |
| P01867 | 404 | Ig gamma-2B chain C region | TM = 1 | 0.0% | 0.0% | 86.6% | 8.9% | 4.5% | 0.0% | 0.0% |
| P02724 | 150 | Glycophorin-A | TM = 1 | 0.0% | 0.0% | 48% | 24% | 15.3% | 12.7% | 0.0% |
| P02725 | 133 | Glycophorin-A | TM = 1 | 0.0% | 0.0% | 46.6% | 39.0.0% | 17.3% | 0.0% | 0.0% |
| P02726 | 120 | Glycophorin-A | TM = 1 | 0.0% | 0.0% | 40.8% | 40.0% | 19.2% | 0.0% | 0.0% |
| P02727 | 129 | Glycophorin-A | TM = 1 | 0.0% | 0.0% | 50.4% | 20.2% | 16.3% | 13.2% | 0.0% |
| P02786 | 760 | Transferrin receptor protein 1 | TM = 1 | 0.0% | 0.0% | 88.4% | 8.8% | 2.8% | 0.0% | 0.0% |
| P03138 | 389 | Large envelope protein | TM = 4 | 0.0% | 0.0% | 63.2% | 14.7% | 22.1% | 0.0% | 0.0% |
| P04441 | 279 | H-2 class II histocompatibility antigen gamma chain | TM = 1 | 0.0% | 0.0% | 80.3% | 10.4% | 9.3% | 0.0% | 0.0% |
| P04921 | 128 | Glycophorin-C | TM = 1 | 0.0% | 0.0% | 44.5% | 36.7% | 18.8% | 0.0% | 0.0% |
| P05067 | 770 | Amyloid beta A4 protein | TM = 1 | 0.0% | 0.0% | 88.6% | 6.1% | 3.1% | 2.2% | 0.0% |
| P06028 | 91 | Glycophorin-B | TM = 1 | 0.0% | 0.0% | 44% | 11% | 24.2% | 20.9% | 0.0% |
| P07204 | 575 | Thrombomodulin | TM = 1 | 0.0% | 0.0% | 86.4% | 6.3% | 4.2% | 3.1% | 0.0% |
| P07359 | 626 | Platelet glycoprotein Ib alpha chain | TM = 1 | 0.0% | 0.0% | 78.1% | 16% | 3.4% | 2.6% | 0.0% |
| P07725 | 236 | T-cell surface glycoprotein CD8 alpha chain | TM = 1 | 0.0% | 0.0% | 69.1% | 11% | 8.9% | 11% | 0.0% |
| P08514 | 1039 | Integrin alpha-IIb | TM = 1 | 0.0% | 0.0% | 92.6% | 1.9% | 2.5% | 3% | 0.0% |
| P08592 | 770 | Amyloid beta A4 protein | TM = 1 | 0.0% | 0.0% | 88.6% | 6.1% | 3.1% | 2.2% | 0.0% |
| P11279 | 417 | Lysosome-associated membrane glycoprotein 1 | TM = 1 | 84.9% | 0.0% | 0.0% | 2.9% | 5.5% | 6.7% | 0.0% |
| P13473 | 410 | Lysosome-associated membrane glycoprotein 2 | TM = 1 | 84.6% | 0.0% | 0.0% | 2.7% | 5.9% | 6.8% | 0.0% |
| P13838 | 378 | Leukosialin | TM = 1 | 0.0% | 0.0% | 59.6% | 32.8% | 6.1% | 1.9% | 0.0% |
| P14221 | 144 | Glycophorin-A | TM = 1 | 0.0% | 0.0% | 47.9% | 36.1% | 16.0.0% | 0.0% | 0.0% |
| P16150 | 400 | Leukosialin | TM = 1 | 0.0% | 0.0% | 58.2% | 31% | 5.8% | 4.8% | 0.0% |
| P17404 | 335 | Chondromodulin-1 | TM = 1 | 0.0% | 0.0% | 0.0% | 0.0% | 6.3% | 0.0% | 93.7% |
| P21583 | 273 | Kit ligand | TM = 1 | 0.0% | 0.0% | 69.2% | 13.2% | 8.4% | 9.2% | 0.0% |
| P42098 | 421 | Zona pellucida sperm-binding protein 3 | TM = 1 | 0.0% | 0.0% | 85.3% | 4.5% | 5.0.0% | 5.2% | 0.0% |
| P51681 | 352 | C-C chemokine receptor type 5 | TM = 7 | 0.0% | 0.0% | 26.1% | 27.0.0% | 46.9% | 0.0% | 0.0% |
| P61073 | 352 | C-X-C chemokine receptor type 4 | TM = 7 | 0.0% | 0.0% | 281% | 29.8% | 42.0.0% | 0.0% | 0.0% |
| P80370 | 383 | Protein delta homolog 1 | TM = 1 | 0.0% | 0.0% | 73.1% | 14.6% | 6.3% | 6.0.0% | 0.0% |
| Q00657 | 2326 | Chondroitin sulfate proteoglycan 4 | TM = 1 | 0.0% | 0.0% | 94.4% | 3.3% | 1.1% | 1.2% | 0.0% |
| Q01455 | 230 | Membrane protein | TM = 3 | 17.0.0% | 0.0% | 0.0% | 57.4% | 25.7% | 0.0% | 0.0% |
| Q07287 | 536 | Zona pellucida sperm-binding protein 4 | TM = 1 | 0.0% | 0.0% | 91.4% | 0.7% | 3.9% | 3.9% | 0.0% |
| Q09163 | 385 | Protein delta homolog 1 | TM = 1 | 0.0% | 0.0% | 73.2% | 14.5% | 6.2% | 6.0.0% | 0.0% |
| Q16790 | 459 | Carbonic anhydrase 9 | TM = 1 | 0.0% | 0.0% | 82.1% | 5.2% | 4.6% | 8.1% | 0.0% |
| Q62765 | 843 | Neuroligin-1 | TM = 1 | 0.0% | 0.0% | 77.3% | 14.8% | 2.5% | 5.3% | 0.0% |
| Q71M36 | 566 | Chondroitin sulfate proteoglycan 5 | TM = 1 | 0.0% | 0.0% | 69.4% | 21.6% | 3.7% | 5.3% | 0.0% |
| Q99075 | 208 | Proheparin-binding EGF-like growth factor | TM = 1 | 0.0% | 0.0% | 67.8% | 11.5% | 11.5% | 9.1% | 0.0% |
Abbreviation: L, Lumenal; N, Nucleoplasmic; E, Extracellular; C, Cytoplasmic; TM, Transmembrane; S, Signal peptide.