Table 2.
Carrier rates by ethnic category* and Hb type: April 2005 to March 2007
| Results for newborns: April 2005 to March 2007 | FAS | FAC | FAD† | FAE | Other Carriers | ||||||
| No. | Rate per 1000 babies screened | No. | Rate per 1000 babies screened | No. | Rate per 1000 babies screened | No. | Rate per 1000 babies screened | No. | Rate per 1000 babies screened | No. of babies screened | |
| White British | 376 | 0.55 | 121 | 0.18 | 249 | 0.37 | 77 | 0.11 | 435 | 0.64 | 679911 |
| Bangladeshi | 10 | 0.68 | 8 | 0.54 | 42 | 2.86 | 610 | 41.54 | 34 | 2.32 | 14686 |
| Pakistani | 28 | 0.87 | 5 | 0.15 | 264 | 8.18 | 61 | 1.89 | 75 | 2.32 | 32289 |
| Chinese | 7 | 1.44 | 1 | 0.21 | 0 | 0.00 | 22 | 4.52 | 14 | 2.88 | 4863 |
| Any other White background | 79 | 1.95 | 19 | 0.47 | 20 | 0.49 | 13 | 0.32 | 36 | 0.89 | 40469 |
| White Irish | 4 | 2.02 | 0 | 0.00 | 0 | 0.00 | 1 | 0.51 | 1 | 0.51 | 1978 |
| White and Asian | 25 | 2.68 | 2 | 0.21 | 21 | 2.25 | 149 | 15.98 | 17 | 1.82 | 9324 |
| Any other Asian background | 40 | 3.39 | 3 | 0.25 | 42 | 3.56 | 77 | 6.52 | 24 | 2.03 | 11806 |
| Indian | 115 | 4.62 | 9 | 0.36 | 176 | 7.07 | 43 | 1.73 | 57 | 2.29 | 24900 |
| Not stated | 1290 | 9.58 | 287 | 2.13 | 137 | 1.02 | 145 | 1.08 | 186 | 1.38 | 134693 |
| Any other ethnic category | 432 | 17.18 | 77 | 3.06 | 34 | 1.35 | 90 | 3.58 | 54 | 2.15 | 25145 |
| Any other mixed background | 339 | 21.00 | 99 | 6.13 | 17 | 1.05 | 70 | 4.34 | 23 | 1.42 | 16141 |
| White and Black Caribbean | 515 | 49.15 | 157 | 14.98 | 5 | 0.48 | 27 | 2.58 | 15 | 1.43 | 10479 |
| White and Black African | 422 | 75.51 | 68 | 12.17 | 1 | 0.18 | 1 | 0.18 | 11 | 1.97 | 5589 |
| Any other Black background | 273 | 81.66 | 64 | 19.14 | 4 | 1.20 | 1 | 0.30 | 11 | 3.29 | 3343 |
| Black Caribbean | 1093 | 86.80 | 383 | 30.42 | 2 | 0.16 | 0 | 0.00 | 26 | 2.06 | 12592 |
| Black African | 4952 | 120.88 | 863 | 21.07 | 8 | 0.20 | 4 | 0.10 | 102 | 2.49 | 40965 |
| Total | 10000 | 9.35 | 2166 | 2.03 | 1022 | 0.96 | 1391 | 1.30 | 1121 | 1.05 | 1069173 |
Birmingham was unable to provide denominators by ethnic category due to variations in coding of ethnic category and laboratory software constraints and their data has been taken out of this table. About 11% of all babies, 10% of carriers and approx 6% of all affected babies are tested in Birmingham.
Note that Portsmouth provided data from April 2006 and Oxford from July 2006 only.
Ethnic category as it appears on the Guthrie card.
Since there are many ‘D’ variants and characterisation may take some time, it is recommended that all ‘D’ variants with the characteristics of D Punjab (the only clinically significant variant) are assumed to be clinically significant and reported. DNA analysis or mass spectrometry can be used to elucidate the diagnosis.