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The effect of vehicle (4% DMSO, 1% Tween 80 in physiological saline) or AM6545 (5 mg·kg−1) on food intake in control (wild-type or C57BL/6J), CB1 receptor knockout (CB1 KO) or CB1/CB2 receptor double knockout (CB1/CB2 KO) mice. Bars represent the mean ± s.e.mean, n = 5–14. **P < 0.01 and ***P < 0.001 denote a significant difference from vehicle control analysed using t-test.
