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Relative gene expression levels in E4.0 blastocysts after microinjection of siCdx2 into MII oocytes and zygotes. Elimination of Cdx2 RNA by microinjection of siCdx2 into mouse (A) MII oocytes and (B) zygotes had similar effects on gene expression levels, as assessed by qRT-PCR. Cdx2 knockdown reduced expression of genes crucial in TE lineage differentiation, with overexpression of pluripotency-related genes. Error bars indicate standard deviation.
