Fig. 3.

Transcription of contractile smooth muscle cell marker genes is reduced in Jag1-SMcko mice. Relative gene expression levels were examined in ductus arteriosus (top) and ascending aorta (bottom) in P0 wild-type (WT) and Jag1-SMcko (CKO) mice. Genes included encode smooth muscle 22α (SM22), smooth muscle actin α2 (SMA2a), smooth muscle actin γ2 (SMA2g), smooth muscle myosin heavy chain (SMMHC), smoothelin (SML) and calponin 2 (CALP). P<0.05 for control versus mutant DA comparisons (Student's t-test); aAo comparisons (except the SMMHC comparison) were not statistically significant. Error bars indicate standard deviation of the mean.