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Toxic effects.
| Type of toxic effect | Cisplatin and vinorelbine (N = 67) | Cisplatin and gemcitabine (N = 67) |
|---|---|---|
| % of patients | ||
| Anemia | ||
| Grade 1–2 | 46.2 | 41.7 |
| Grade 3–4 | 8.9 | 7.4 |
| Neutropenia | ||
| Grade 1–2 | 44.7 | 35.8 |
| Grade 3–4 | 1.4 | 8.9 |
| Febrile neutropenia | 8.9* | 1.4 |
| Thrombocytopenia | ||
| Grade 1–2 | 5.9 | 11.9 |
| Grade 3–4 | 1.4 | 8.9* |
| Nausea and vomiting | ||
| Grade 1–2 | 65.6 | 58.2 |
| Grade 3–4 | 4.4 | 2.9 |
Pearson chi-square test.
p < 0.05.
