Table 1.

Frequency Distribution of the Genotypes Defined by Carrying the Minor Alleles of One of the Two SNPs of FOXO1A or One of the Three SNPS of FOXO3A Based on the Dominant Model, and the Estimates of the Odds Ratio of Survival Probability (RS) from Middle Age to Age 100+ Measuring the General Effects of the Genotypes

	Women				Men
Genotypes	Cent. %car.	Contr %car.	RS (95% CI)	p	Cent. %car.	Contr %car.	RS (95% CI)	p
Carrying minor allele of 1A-209	42.3	51.3	0.70 (0.53–0.91)	0.0073	41.8	49.5	0.73 (0.51–1.05)	0.093
Carrying minor allele of 1A-213	57.8	65.8	0.71 (0.54–0.91)	0.0152	58.8	68.6	0.65 (0.45–0.95)	0.025
Carrying minor allele of 3A-310	51.9	39.3	1.67 (1.27–2.18)	0.0002	55.5	43.0	1.65 (1.19–2.30)	0.003
Carrying minor allele of 3A-292	51.7	39.8	1.62 (1.24–2.12)	0.0004	56.3	42.7	1.73 (1.24–2.41)	0.001
Carrying minor allele of 3A-936	49.5	37.1	1.66 (1.26–2.18)	0.0003	51.9	40.2	1.61 (1.16–2.24)	0.005

Note: Sample size—centenarians: 578 women and 182 men; middle-age controls: 378 women and 682 men, all Han Chinese from Southern China. CI = confidence interval. Cent. %car. = Percentage of centenarians who carry the minor allele; Contr %car. = Percentage of middle-age controls who carry the minor allele; SNP = single-nucleotide polymorphisms.