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. Author manuscript; available in PMC: 2011 Nov 25.
Published in final edited form as: J Med Chem. 2010 Oct 22;53(22):7958–7966. doi: 10.1021/jm100593s

Figure 1.

Figure 1

Panel A: Antiviral effects of compounds against poliovirus. HeLa S3 cells were incubated with 2–7 for 1 h at the concentrations shown, and subsequently infected with at least 106 PFU of PV. After infection for 15 min, fresh media containing 2–7 was added and the infection continued for 6 h. Cell-associated virus was titered by plaque assay. Panels B–D: Cytotoxicity to HeLa S3 cells after treatment with 2–7 for 7 h (B), 24 h (C) or 48 h (D).