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. 2010 Nov 4;4:129. doi: 10.3389/fncel.2010.00129

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Copyright © 2010 Fahmy and Moftah.

This is an open-access article subject to an exclusive license agreement between the authors and the Frontiers Research Foundation, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are credited.

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Double labeling of FGF-2 and GFAP in brain stem after 1 week of lesion. (A) Sham operated (B) Lesioned cases. Intense FGF-2 and GFAP immunoreactivity is obvious in cells lining the fourth ventricle and cells surrounding them compared to sham-operated animals. The blue color in upper panel is a nuclear marker and orange color in lower panel (arrow) shows the colocalization between FGF-2 and GFAP showing the presence of FGF-2 in glial cells ×63. (C) Percentages of labeling intensity of FGF-2 and GFAP immunoreactivity compared to sham-operated cases in Brain Stem. The graph shows significant increase in FGF-2.ocalization, which was time-dependent within 1, 2, and 6 weeks after spinal cord lesion. GFAP slightly increased in week 6.