Table 2. Characteristics of patients by treatment group.
| Surgery alone (n=14) | Surgery with adjuvant RT (n=110) | Definitive RT alone (n=24) | Definitive RT with CT (n=47) | P-value a | |
|---|---|---|---|---|---|
| Mean age at diagnosis (range) | 67.1 (44–84) | 58.2 (34–84) | 60.7 (38–84) | 58.2 (38–83) | 0.03 |
| Gender | |||||
| Males | 10 (71%) | 85 (77%) | 22 (92%) | 42 (89%) | 0.1 |
| Females | 4 (29%) | 25 (23%) | 2 (8%) | 5 (11%) | |
| Location | |||||
| Tonsil | 9 (65%) | 79 (72%) | 16 (67%) | 20 (43%) | 0.02 |
| Base of tongue | 2 (14%) | 16 (15%) | 2 (8%) | 16 (34%) | |
| Other subsites | 3 (21%) | 15 (14%) | 6 (25%) | 11 (23%) | |
| Stage | |||||
| 3 | 8 (57%) | 39 (35%) | 9 (38%) | 22 (47%) | 0.3 |
| 4 | 6 (43%) | 71 (65%) | 15 (63%) | 25 (53%) | |
| Grade | |||||
| 1, 2 | 10 (71%) | 62 (56%) | 15 (63%) | 31 (66%) | 0.5 |
| 3 | 4 (29%) | 48 (44%) | 9 (38%) | 16 (34%) | |
| HPV status | |||||
| Negative | 10 (71%) | 63 (57%) | 14 (58%) | 25 (53%) | 0.7 |
| Positive | 4 (29%) | 47 (43%) | 10 (42%) | 22 (47%) | |
Abbreviations: CT=chemotherapy; HPV=human papillomavirus; RT=radiation therapy.
a
Test for heterogeneity.