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. 2010 Sep 28;103(9):1356–1361. doi: 10.1038/sj.bjc.6605919

Table 2. The relationship between clinico-pathological variables and survival in patients undergoing potentially curative resection for colorectal cancer; univariate survival analysis.

    Cancer-specific survival
Overall survival
Variable 320 (%) Hazard ratio (95% CI) P-value Hazard ratio (95% CI) P-value
Age
 ⩽64 111 (35)        
 65–74 102 (32)        
 ⩾75 107 (33) 1.66 (1.26, 2.18) 0.001 1.80 (1.45, 2.23) <0.001
           
Sex
 Male 170 (53)        
 Female 150 (47) 1.30 (0.84, 2.01) 0.25 1.18 (0.84, 1.66) 0.34
           
Deprivation
 1–2 12 (4)        
 3–5 99 (31)        
 6–7 209 (65) 1.11 (0.74, 1.65) 0.46 0.98 (0.72, 1.32) 0.77
           
Smoking
 Never 135 (42)        
 Current/previous 185 (58) 1.62 (1.02, 2.55) 0.04 1.67 (1.17, 2.39) 0.004
           
Presentation
 Elective 307 (96)        
 Emergency 13 (4) 3.93 (1.80, 8.56) <0.001 3.00 (1.53, 5.94) 0.001
           
Tumour site
 Colon 197 (62)        
 Rectum 123 (38) 0.84 (0.53, 1.32) 0.45 1.09 (0.77, 1.54) 0.62
           
Differentiation
 Well/ moderate 286 (89)        
 Poor 34 (11) 1.26 (0.63, 2.52) 0.51 1.58 (0.96, 2.59) 0.07
           
Dukes stage
 Dukes A 38 (12)        
 Dukes B 153 (48)        
 Dukes C 129 (40) 2.21 (1.51, 3.21) <0.001 1.60 (1.21, 2.10) 0.004
           
Adjuvant therapy
 No 254 (79)        
 Yes 66 (21) 1.00 (0.59, 1.69) 0.99 0.90 (0.59, 1.37) 0.61
           
mGPS
 Low (0) 194 (61)        
 Intermediate (1) 90 (28)        
 High (2) 36 (11) 1.71 (1.29, 2.27) <0.001 1.60 (1.28, 2.01) <0.001
           
POSSUM physiology score
 Group 1 (11–14) 109 (34)        
 Group 2 (15–20) 134 (42)        
 Group 3 (21–30) 69 (21)        
 Group 4 (>30) 8 (3) 1.73 (1.33, 2.25) <0.001 1.59 (1.29, 1.96) <0.001

Abbreviation: CI=confidence interval.