Table 3. The relationship between clinico-pathological variables and survival in patients undergoing potentially curative resection for colorectal cancer; multivariate survival analysis.
|
Cancer-specific survival
|
Overall survival
|
|||
|---|---|---|---|---|
| Variable | Hazard ratio (95% CI) | P-value | Hazard ratio (95% CI) | P-value |
| Age | 1.46 (1.10, 1.94) | <0.001 | 1.64 (1.32, 2.05) | <0.001 |
| Smoking | 1.46 (0.92, 2.32) | 0.10 | 1.52 (1.06, 2.18) | 0.02 |
| Presentation | 2.08 (0.91, 4.76) | 0.08 | 1.70 (0.84, 3.45) | 0.14 |
| Dukes | 2.39 (1.59, 3.59) | <0.001 | 1.64 (1.22, 2.20) | <0.001 |
| mGPS | 1.78 (1.32, 2.41) | <0.001 | 1.60 (1.26, 2.02) | <0.001 |
| POSSUM physiology score | 1.38 (1.05, 1.82) | 0.02 | 1.27 (1.02, 1.58) | 0.03 |
Abbreviations: CI=confidence interval; mGPS=modified Glasgow Prognostic Score; POSSUM=physiological and operative severity score for the enumeration of mortality and morbidity.