Table 4. The relationships between POSSUM physiology score and clinico-pathological characteristics in patients undergoing potentially curative resection for colorectal cancer.
Group 1 | Group 2 | Group 3 | Group 4 | ||
---|---|---|---|---|---|
11–14 | 15–20 | 21–30 | >30 | ||
Variable | (n=109) | (n=134) | (n=69) | (n=8) | P-value |
POSSUM variables | |||||
Cardiac (1/2/4/8) | 82/27/0/0 | 66/60/8/0 | 6/40/20/3 | 0/1/5/2 | <0.001 |
Resp. (1/2/4/8) | 86/23/0/0 | 80/39/13/2 | 32/15/19/3 | 2/2/3/1 | <0.001 |
ECG (1/4/8) | 109/0/0 | 125/3/6 | 26/12/31 | 2/1/5 | <0.001 |
SBP (1/2/4/8) | 59/50/0/0 | 43/75/15/1 | 26/35/7/1 | 0/4/4/0 | <0.001 |
Pulse (1/2/4/8) | 83/26/0/0 | 80/46/8/0 | 37/27/5/0 | 4/3/1/0 | 0.01 |
Hb (1/2/4/8) | 71/37/1/0 | 33/36/43/22 | 14/14/13/28 | 0/3/2/3 | <0.001 |
WCC (1/2/4) | 104/4/1 | 103/28/3 | 49/19/1 | 1/6/1 | <0.001 |
Sodium (1/2/4/8) | 107/2/0/0 | 121/10/3/0 | 62/5/2/0 | 5/2/1/0 | 0.008 |
Potassium (1/2/4/8) | 106/3/0/0 | 123/7/4/0 | 64/4/1/0 | 6/1/1/0 | 0.11 |
Urea (1/2/4/8) | 107/2/0/0 | 114/16/4/0 | 62/6/1/0 | 2/1/4/1 | <0.001 |
GCS (1/2/4/8) | 109/0/0/0 | 134/0/0/0 | 69/0/0/0 | 8/0/0/0 | N/A |
Age | |||||
⩽64/65–74/⩾75 | 57/31/21 | 41/41/52 | 13/27/29 | 0/3/5 | <0.001 |
Sex | |||||
Male/female | 64/45 | 64/70 | 38/31 | 4/4 | 0.38 |
Smoking | |||||
Never/current or ex | 54/55 | 55/79 | 25/44 | 1/7 | 0.09 |
Presentation | |||||
Elective/emergency | 107/2 | 127/7 | 66/3 | 7/1 | 0.34 |
Tumour site | |||||
Colon/rectum | 51/58 | 85/49 | 54/15 | 7/1 | <0.001 |
Deprivation | |||||
1–2/3–5/6–7 | 5/42/62 | 5/39/93 | 2/19/48 | 0/2/6 | 0.47 |
Differentiation | |||||
Well or mod/poor | 101/8 | 122/12 | 57/12 | 6/2 | 0.08 |
Dukes stage | |||||
A/B/C | 22/46/41 | 13/67/54 | 3/37/29 | 0/3/5 | 0.03 |
Glasgow Prognostic Score | |||||
mGPS 0/1/2 | 80/22/7 | 77/44/13 | 34/21/14 | 3/3/2 | 0.006 |
Abbreviations: mGPS=modified Glasgow Prognostic Score; POSSUM=physiological and operative severity score for the enumeration of mortality and morbidity.