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. 2010 Sep 28;103(9):1356–1361. doi: 10.1038/sj.bjc.6605919

Table 4. The relationships between POSSUM physiology score and clinico-pathological characteristics in patients undergoing potentially curative resection for colorectal cancer.

  Group 1 Group 2 Group 3 Group 4  
  11–14 15–20 21–30 >30  
Variable (n=109) (n=134) (n=69) (n=8) P-value
POSSUM variables
 Cardiac (1/2/4/8) 82/27/0/0 66/60/8/0 6/40/20/3 0/1/5/2 <0.001
 Resp. (1/2/4/8) 86/23/0/0 80/39/13/2 32/15/19/3 2/2/3/1 <0.001
 ECG (1/4/8) 109/0/0 125/3/6 26/12/31 2/1/5 <0.001
 SBP (1/2/4/8) 59/50/0/0 43/75/15/1 26/35/7/1 0/4/4/0 <0.001
 Pulse (1/2/4/8) 83/26/0/0 80/46/8/0 37/27/5/0 4/3/1/0 0.01
 Hb (1/2/4/8) 71/37/1/0 33/36/43/22 14/14/13/28 0/3/2/3 <0.001
 WCC (1/2/4) 104/4/1 103/28/3 49/19/1 1/6/1 <0.001
 Sodium (1/2/4/8) 107/2/0/0 121/10/3/0 62/5/2/0 5/2/1/0 0.008
 Potassium (1/2/4/8) 106/3/0/0 123/7/4/0 64/4/1/0 6/1/1/0 0.11
 Urea (1/2/4/8) 107/2/0/0 114/16/4/0 62/6/1/0 2/1/4/1 <0.001
 GCS (1/2/4/8) 109/0/0/0 134/0/0/0 69/0/0/0 8/0/0/0 N/A
           
Age
 ⩽64/65–74/⩾75 57/31/21 41/41/52 13/27/29 0/3/5 <0.001
           
Sex
 Male/female 64/45 64/70 38/31 4/4 0.38
           
Smoking
 Never/current or ex 54/55 55/79 25/44 1/7 0.09
           
Presentation
 Elective/emergency 107/2 127/7 66/3 7/1 0.34
           
Tumour site
 Colon/rectum 51/58 85/49 54/15 7/1 <0.001
           
Deprivation
 1–2/3–5/6–7 5/42/62 5/39/93 2/19/48 0/2/6 0.47
           
Differentiation
 Well or mod/poor 101/8 122/12 57/12 6/2 0.08
           
Dukes stage
 A/B/C 22/46/41 13/67/54 3/37/29 0/3/5 0.03
           
Glasgow Prognostic Score
 mGPS 0/1/2 80/22/7 77/44/13 34/21/14 3/3/2 0.006

Abbreviations: mGPS=modified Glasgow Prognostic Score; POSSUM=physiological and operative severity score for the enumeration of mortality and morbidity.