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. 2010 Oct 5;103(9):1343–1348. doi: 10.1038/sj.bjc.6605928

Table 2. Percentages of toxicity of the docetaxel, cisplatin, tegafur/uracil, and leucovorin regimen.

  Patients (n=45)
Cycles (n=271)
  Grade
Grade
Grade
Grade
Toxicity 1 2 3 4 1 2 3 4
Haematological
 Neutropenia 4a 11 33 18 11b 13 17 6
 Leukopenia 7 31 24 9 17 16 10 1
 Thrombocytopenia 18 9 2 2 21 2 0.4 0.4
 Febrile neutropeniac 0 0 4 0 0 0 1 0
 Anaemia 2 58 22 0 4 27 5 0
                 
Gastrointestinal
 Nausea 31 22 7 0 19 6 1 0
 Vomiting 22 29 4 0 12 7 1 0
 Diarrhoea 22 33 13 2 16 14 3 0
 Stomatitis 13 22 7 0 5 11 4 0
 Anorexia 24 24 4 0 18 6 8 0
 Weight loss 20 16 2 0 10 6 0.4 0
                 
Neurosensory 7 2 0 0 10 1 0 0
                 
Others
 Hand and foot syndrome 4 4 0 0 3 5 0 0
 Fever 16 7 0 0 6 1 0 0
 Infections 11 16 20 0 5 5 7 0
 Alopecia 36 9 0 0 31 5 0 0
a

All numbers are percentages of the 45 patients.

b

All numbers are percentages of the 271 cycles given.

c

Febrile neutropenia was defined as fever of unknown origin without clinically or microbiologically documented infection with absolute neutrophil count <1.0 × 109/l and fever ⩾38.5°C, according to the National Cancer Institute Common Terminology Criteria for Adverse Events 3.0.