Table 1. Antigen-specific immune responses.
| Patient | 1 | 2 | 3 | 4 | 5 | 6 | 7 |
|---|---|---|---|---|---|---|---|
| KLH CD4+ response | + | + | + | + | + | + | + |
| KLH antibody response | − | − | − | − | + | + | − |
| CEA-tetramers peripheral blood | − | − | − | − | − | − | − |
| CEA-tetramers DTH | − | + | nt | − | − | − | + |
| CEA-specific IFN-γ response in DTH | + | + | + | − | − | − | + |
Abbreviations: CEA=carcinoembryonic antigen; DTH=delayed type hypersensitivity; IFN=interferon; KLH=keyhole limpet haemocyanin; nt=not tested.
Summary of all tested KLH and CEA-specific immune responses upon vaccination and oxaliplatin/capecitabine treatment.