Table 4.
Responses to an OGTT in chronic stroke subjects and controls with normal (NGT) and impaired (IGT) glucose tolerance
| Stroke subjects (n = 12) | IGT control (n = 12) | NGT control (n = 12) | |
|---|---|---|---|
| FPG (mmol/L) | 5.7 ± 0.15*, † | 5.2 ± 0.09 | 5.3 ± 0.13 |
| G120 (mmol/L) | 10.2 ± 0.76‖ | 9.5 ± 0.28‖ | 5.6 ± 0.36 |
| Glucose AUC (mmol/L/120min) | 1,158 ± 60‖ | 1,073 ± 31‖ | 807 ± 47 |
| Fasting Insulin (pmol/L) | 180 ± 27§, ‡ | 94 ± 9 | 82 ± 10 |
| I120 (pmol/L) | 1,125 ± 124‖ | 1,024 ± 183‖ | 383 ± 67 |
| Insulin AUC (pmol/L/120min) | 104,535 ± 10,573† | 107,947 ± 19,155† | 59,370 ± 7,212 |
| ISIM | 1.46 ± 0.21‖ | 2.26 ± 0.49† | 3.63 ± 0.40 |
Data are presented as mean±SEM.
*,§
Significant difference, compared to IGT controls (*P <0.05, §P <0.01);
†,‡,‖
significant difference, compared to NGT controls (†P <0.05, ‡P <0.01, ‖P <0.001).
FPG, fasting plasma glucose; G120, 120-minute glucose; AUC, area under the curve; I120, 120-minute insulin; ISIM, insulin sensitivity index calculated by using the method of Matsuda and DeFronzo [22].