Figure 5. MSP1-specific IgG antibody-secreting cells (ASC) appear transiently in peripheral blood during infection.

The frequencies of ASC were determined by direct ELISpot assays as described in the experimental procedures. The numbers of MSP1-specific IgG ASC in peripheral blood, spleen and bone marrow following both a primary and secondary infection are presented as ASC per ml of blood, per spleen and per two femurs respectively. The values and error bars shown are the means and the standard errors of the mean (SEM) of 5 to 7 mice.