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Genotype distributions and allele frequencies for 314C/T polymorphism of HNMT gene from five association studies in asthma (asthmatic patients vs. control group)
| Asthma (n = 1049) | Control group (n = 1242) | P value | |
|---|---|---|---|
| CC | 806 (76.8) | 1011 (81.4) | 0.007* |
| CT | 221 (21.1) | 219 (17.6) | |
| TT | 22 (2.1) | 12 (1.0) | |
| C | 1833 (87.4) | 2241 (90.2) | 0.002* |
| T | 265 (12.6) | 243 (9.8) | |
* Indicates significance: for genotypes: χ2 = 9.839, df = 2; for alleles: χ2 = 9.075, df = 1, OR = 1.33, 95%CI: 1.108-1.604.
