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. 2010 Oct 28;29(1):138. doi: 10.1186/1756-9966-29-138

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Copyright ©2010 Zhou et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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DKK-1 concentration in sera (A) and cerebral fluid (B) samples determined by ELISA in patients with tumors and in healthy controls. *, difference between the glioma group and neuronal benign tumor group. **, difference between the glioma group and normal control group. ***, difference between the neuronal benign tumor group and healthy control group. The DKK-1 concentration in cerebral fluid is increased in glioma, and differences may exist among different glioma grades, suggesting the role of DKK-1 in glioma pathogenesis.