Table 3.

Gastric acid output, fasting serum gastrin, and Helicobacter pylori status following curative resection

Postoperative Parameter	Number (percent)(1)
	Normosecretors	Hypersecretors
	(n=19)	Moderate (n=17)	Extreme (n=14)
BAO at 3–6 mos (mEq/h)(2)	5.7 ± 1.3	13.9 ± 2.1(a)	21.3 ± 3.0(b)
BAO at 3–6 mos (% of pre-op value)(2)	25.0 ± 7.7	46.4 ± 10.0(a)	46.5 ± 10.0(a)
MAO at 3–6 mos (mEq/h)	31.6 ± 5.8	44.8 ± 5.4	63.5 ± 9.1(a)
MAO at 3–6 mos (% of pre-op value)(2)	65.1 ± 8.7	80.9 ± 9.2	70.9 ± 10.4
Highest BAO (mEq/h)(3)	7.1 ± 1.1	17.7 ± 1.7(b)	33.1 ± 4.0(c, d)
Highest BAO (% of pre-op value)(4)	32.6 ± 8.4	68.4 ± 9.2	67.2 ± 9.6
Highest MAO (mEq/h)(3)	34.9 ± 6.6	52.8 ± 6.8	82.7 ± 9.4(c)
Highest MAO (% of pre-op value)(4)	71.5 ± 12.4	90.5 ± 9.2	98.2 ± 9.9
Fasting serum gastrin immediate post-op (pg/ml)	69.0 ± 6.4	102.5 ± 26.8	72.1 ± 5.5
Delta secretin immediate post-op (pg/ml)(5)	37.3 ± 18.1	22.3 ± 5.5	31.2 ± 6.2
Fasting serum gastrin at time of highest BAO (pg/ml)	58.6 ± 8.1	53.6 ± 6.3	85.1 ± 12.9
Delta secretin at time of highest BAO (pg/ml)(5)	28.3 ± 17.6	28.8 ± 5.6	52.5 ± 15.1
Helicobacter pylori status (% present)(6)	3 (16%)	2 (12%)	0

Compared to normosecretors:

^(a)P <0.01,

^(b)P <0.001,

^(c)P <0.0001; compared to moderate hypersecretors:

^(d)P <0.0001.

⁽¹⁾Number and percent are as defined in Table 1 legend.

⁽²⁾Basal acid output (BAO) or maximal acid output (MAO) at 3 to 6 months post-curative resection are expressed as a percentage of the pre-operative value.

⁽³⁾Highest BAO is as defined in Table 1 legend. Highest MAO is similarly defined.

⁽⁴⁾Highest BAO or MAO expressed as a percentage of the pre-operative value.

⁽⁵⁾Immediate post-op means within two weeks of curative resection. Delta secretin is the increase in serum gastrin following secretin injection [28].

⁽⁶⁾H. pylori status refers to the results of evaluation for the presence of H. pylori as defined in METHODS post-curative resection and prior to or at time of highest BAO.