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. Author manuscript; available in PMC: 2012 Mar 1.
Published in final edited form as: Peptides. 2010 Jun 15;32(3):595–600. doi: 10.1016/j.peptides.2010.06.005

Table 2.

Synergism factor and binding affinities of mixtures of proteins at 0.2:1 ratio.

Toxins Cyt1Aa:Cry4Ba Predicted LC50 (ng/ml) Experimental LC50 (ng/ml) SFa
wt:wt 75.2 8.5 (6.5–10.8)b 8.8
K198A:wt 74.5 21.0 (10.1–30.1) 3.5
E204A:wt 66.7 25.2 (20.1–32.3) 2.6
K225A:wt 75.1 41.4 (31.1–52.3) 1.8
wt:α8M2 218.9 38.4 (32.7– 44.7) 5.7
E204:α8M2 158.3 77.2 (67.1–88.9) 2
a

Synergism factor (Predicted LC50/Experimental LC50)

b

95% fiducial limits.