Skip to main content
. Author manuscript; available in PMC: 2012 Mar 1.
Published in final edited form as: Inflamm Bowel Dis. 2010 Aug 18;17(3):720–731. doi: 10.1002/ibd.21419

Figure 5. NF-κB site is essential for TNF-α-induced repressor effect on hNHE2 promoter.

Figure 5

The nucleotide substitutions of the M1 and M2 mutants were introduced into the wild-type NHE2 promoter construct, p−890/+150. Wild-type and mutated constructs were transiently transfected into C2BBe1 cells, and reporter gene activity was measured and analyzed as described in Materials and Methods. The data shown are representative of at least three separate experiments performed in triplicates. *, P < 0.05.