Table 2.
Clinical findings at hospital admission and respiratory variables of patients with confirmed S-OIV infection
| Clinical findings and symptoms | n (%) |
| Total of patients | 8 |
| SIRS | 8 (100) |
| Fever or hypothermia (T >38 or <36°C) | 8 (100) |
| Tachypnea (RR >20 breaths/min) | 8 (100) |
| Tachycardia (HR >100 beats/min) | 5 (63) |
| Leukocytosis (>10 000 mm3) | 6 (75) |
| Leukopenia (<4000/mm3) | 2 (25) |
| Hypotension (systolic blood pressure < 90 mmHg) on admission | 2 (25) |
| Hypoxemia on admission | 8 (100) |
| SpO2 < 90% | 4 (50) |
| 90% < SpO2 < 95% | 4 (50) |
| SpO2 > 95% | 0 (0) |
| Number of quadrants with opacities in initial radiography | |
| None | 2 (25) |
| One quadrant | 3 (38) |
| Two quadrants | 3 (38) |
| Three or four quadrants | 0 (0) |
| Number of quadrants with opacities in radiography after 24 h admission | |
| None | 0 (0) |
| One quadrant | 1 (13) |
| Two quadrants | 2 (25) |
| Three or four quadrants | 5 (63) |
| Invasive mechanical ventilation/noninvasive ventilation | 5 (63) |
| Timing of orotracheal intubation (h) related to ICU admission | |
| Before ICU admission | 1 (13) |
| 0–24 | 3 (38) |
| 24–48 | 0 (0) |
| >48 | 1 (13) |
| Respiratory and ventilatory variables in five mechanically ventilated patients | 5 (100) |
| PaO2/FiO2 < 200, median (range) | 118 (64–170) |
| PEEP, median (range) | 13 (10–20) |
| Pressure-cycled ventilation | 5 (100) |
| Open-lung approach | 5 (100) |
| Neuromuscular blockade | 2 (40) |
| Recruitment maneuvers | 5 (100) |
| Refractory hypoxemia | 5 (100) |
| Apache II score (median) | 24 |
| SAPS II (median) | 52 |
| Admission SOFA (median) | 10 |
| Organ dysfunction at admission | |
| Respiratory failure | 8 (100) |
| Liver failure | 0 (0) |
| Central nervous system failure | 4 (50) |
| Renal failure | 6 (75) |
| Hematological failure | 5 (63) |
| Cardiovascular failure | 6 (75) |
| Use of vasopressor and inotropic | |
| Norepinephrine | 6 (75) |
| Vasopressin | 3 (37) |
| Dobutamine | 4 (50) |
| SOFA on day 2 (median) | 16 |
| Use of antibiotics | 8 (100) |
| Onset of oseltamivir therapy after hospital admission (h) | |
| 0–6 | 2 (25) |
| 6–12 | 4 (50) |
| 12–24 | 2 (25) |
| >24 | 1 (13) |
| Use of corticosteroids | 8 (100) |
| Time from hospital admission to ICU arrival (h), median (range) | 21 (7–60) |
| Death | 5 (63) |
| Days from ICU to death, median (range) | 3 (1–8) |
S-OIV, swine-origin influenza A virus; SIRS, systemic inflammatory response syndrome; RR, respiratory rate; HR, heart rate; SpO2, oxygen peripheral saturation; ICU, intensive care unit; PaO2, oxygen arterial pressure; FiO2, oxygen inspired fraction; SAPS II, Simplified Acute Physiology Score II; SOFA, Sequential Organ Failure Assessment; T, temperature; PEEP, positive end-expiratory pressure.