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. 2010 May 28;21(12):2333–2341. doi: 10.1093/annonc/mdq254

Table 4.

Pathological and microbiological findings in patients with neoplasm who died with H1N1 infection

Patient/age Gender Neoplasm Metastasis Lung pathology Bronchopneumonia Bacterial culture Lung PCR for bacteria Extrapulmonary findings
01/58 years F Myelofibrosis Absent DAD and alveolar hemorrhage Present Streptococcus pneumoniae Positive Acute tubular necrosis, bone marrow fibrosis, liver hemosiderosis, white pulp depletion in spleen
02/56 years F Rectal melanoma Pleura, lung, liver, heart, lymph nodes, adrenal glands Exudative DAD Present S. pneumoniae Positive Acute tubular necrosis, liver necrosis, white pulp depletion in spleen
03/56 years F Breast carcinoma Brain, lung, lymph nodes, diaphragm Exudative DAD Absent Negative Negative Acute tubular necrosis, brain necrosis, hypocellular bone marrow, white pulp depletion in spleen
04/60 years M Esophagus cancer Neck lymph nodes No virus-related pulmonary changes Present S. pneumoniae and Pseudomonas aeruginosa Negative Acute tubular necrosis, white pulp depletion in spleen, hypocellular bone marrow, lung thromboembolism
05/55 years M Esophagus cancer Liver, kidney, thoracic lymph nodes DAD and necrotizing bronchiolitis Present S. pneumoniae Negative Liver necrosis, hypocellular bone marrow, white pulp depletion in spleen lung thromboembolism

F, female; M, male; DAD, diffuse alveolar damage.

HHS Vulnerability Disclosure