Table 4.
Pathological and microbiological findings in patients with neoplasm who died with H1N1 infection
Patient/age | Gender | Neoplasm | Metastasis | Lung pathology | Bronchopneumonia | Bacterial culture | Lung PCR for bacteria | Extrapulmonary findings |
01/58 years | F | Myelofibrosis | Absent | DAD and alveolar hemorrhage | Present | Streptococcus pneumoniae | Positive | Acute tubular necrosis, bone marrow fibrosis, liver hemosiderosis, white pulp depletion in spleen |
02/56 years | F | Rectal melanoma | Pleura, lung, liver, heart, lymph nodes, adrenal glands | Exudative DAD | Present | S. pneumoniae | Positive | Acute tubular necrosis, liver necrosis, white pulp depletion in spleen |
03/56 years | F | Breast carcinoma | Brain, lung, lymph nodes, diaphragm | Exudative DAD | Absent | Negative | Negative | Acute tubular necrosis, brain necrosis, hypocellular bone marrow, white pulp depletion in spleen |
04/60 years | M | Esophagus cancer | Neck lymph nodes | No virus-related pulmonary changes | Present | S. pneumoniae and Pseudomonas aeruginosa | Negative | Acute tubular necrosis, white pulp depletion in spleen, hypocellular bone marrow, lung thromboembolism |
05/55 years | M | Esophagus cancer | Liver, kidney, thoracic lymph nodes | DAD and necrotizing bronchiolitis | Present | S. pneumoniae | Negative | Liver necrosis, hypocellular bone marrow, white pulp depletion in spleen lung thromboembolism |
F, female; M, male; DAD, diffuse alveolar damage.