Table 3.
Univariate Analyses of Demographic and Baseline Characteristics as Potential Risk Factors for Venous Stasis Syndrome, Venous Outflow Obstruction and Venous Valvular Incompetence
| Variable $$ | Endpoints |
||
|---|---|---|---|
| Venous Stasis Syndrome |
Venous Outflow Obstruction |
Venous Valvular Incompetence |
|
| ---------------------- Odds Ratios (95% Confidence Intervals) ----------------- | |||
| Age at Visit Δ per 10 years | 1.2 (1.1, 1.4)† | 1.7 (1.3, 2.2)† | 1.1 (0.96, 1.3) |
| Male | 1.2 (0.8, 1.8) | 2.1 (1.05, 4.0)* | 1.4 (0.9, 2.1) |
| Time Since VTE Event | |||
| Δ per 5 years | 1.2 (1.03, 1.5)* | ||
| 10 vs 5 | 0.6 (0.4, 0.96)* | 0.7 (0.5, 1.01) | |
| 15 vs 10 | 0.9 (0.6, 1.2) | 1.0 (0.8, 1.2) | |
| 20 vs 15 | 1.3 (1.03, 1.7)* | 1.4 (1.1, 1.7)* | |
| 25 vs 20 | 2.0 (1.3, 3.1)* | 2.0 (1.3, 2.9)* | |
| VTE Case | 5.7 (3.5, 9.5)‡ | 3.3 (1.4, 7.6)† | 4.0 (2.4, 6.6)‡ |
| Unadjusted | |||
| VTE Case | 6.4 (3.8, 10.8)‡ | 3.2 (1.3, 7.8)* | 3.6 (2.1, 6.2)‡ |
| Adjusted for age, gender, and time since event | |||
| BMI | 1.1 (1.04, 1.1)‡ | 1.0 (0.9, 1.1) | 1.0 (0.99, 1.1) |
| Prior Superficial Vein Thrombosis | 4.2 (1.6, 10.7)† | 1.1 (0.3, 3.7) | 2.1 (0.9, 4.8) |
| Prior Varicose Veins | 3.7 (2.1, 6.5)‡ | 2.0 (1.00, 4.2) | 3.0 (1.8, 5.2)‡ |
| Lung Disease / Pulmonary Hypertension | 1.5 (0.4, 5.4) | 1.2 (0.5, 3.2) | 2.3 (0.9, 6.0) |
|
Prior venous stasis syndrome prior to the incident event |
2.2 (0.7, 7.1) | 6.4 (2.1, 19.8)† | 6.9 (2.0, 24.2)† |
Only variables that were significant in at least one analysis are shown
p-value<0.05
p-value<0.01
p-value<0.001