Fig. 2.

Increased severity of arthritis in CD200R1^−/− mice. CD200R1^−/− and wild-type mice were immunized with chicken type II chicken collagen in Freund's complete adjuvant (CFA) on day 0. Arthritis incidence was calculated based on three independent experiments and correspond to mean ± standard error of the mean (s.e.m.) (n = 24 and 29 for CD200R1^−/− and wild-type controls, respectively). Inset shows cumulative clinical scores of arthritic mice up to day 50 post-immunization, as indicated by area under the curve. Data representative of three independent experiments.