Table 6.
p Values from multivariate and univariate tests comparing three study groups (HCV–/SUD–, HCV+/SUD–, and HCV+/SUD+) on neuropsychological performance, with estimated cognitive reserve, current depressive symptom severity, and current pain ratings entered as covariates
Covariates | Estimated cognitive reserve1 |
Current depressive symptom severity 2 |
Current pain rating3 |
---|---|---|---|
Verbal Memory | .048 | .018 | .053P |
CVLT-II Total Immediate | .029 | .005 | .016P |
CVLT-II Long Delay Free Recall | .165 | .144 | .196 |
CVLT-II Recognition Correct Hits | .057E | .510D | .516 |
Auditory Attention | .163W | .036 | .047 |
WAIS-III Digit Span | .076W | .012 | .010 |
WAIS-III Letter Number Sequencing | .171W | .057 | .128P |
Speeded Visual Information | .002W | .001 | .004 |
Processing/Attention | |||
Trails A | .177 | .511 | .414 |
Trails B | .219EW | .205 | .282 |
WAIS-III Digit Symbol | .000 | .000 | .000 |
D-KEFS CWIT Inhibition | 474W | .334 | .389 |
D-KEFS CWIT Switching | .643W | .340 | .547P |
Reasoning/Mental Flexibility | .181W | .011D | .017P |
D-KEFS Sorting Correct Sorts | .061 | .005D | .003 |
D-KEFS Proverbs Free Inquiry | .649EW | .018 | .033 |
WAIS-III Matrix Reasoning | .178W | .017 | .087P |
Note. p Values are displayed for each test controlling for covariates. Rows with cognitive domain names include multivariate effects (Wilks Λ, MANCOVAs), with the three study groups and covariates entered as independent variables and standardized scores for each relevant subtest within a cognitive domain entered as multiple dependent variables. Rows with subtest names include univariate effects (F tests), with the three study groups and covariates entered as independent variables and individual subtests entered as dependent variables. Covariates with p values of <.05 are indicated by D = depression, W = WRAT3, E = education, and P = pain. CWIT = Color–Word Interference Test.
Cognitive reserve was estimated using years of education and standard scores on WRAT3 Reading.
Depression was measured using the Beck Depression Inventory, second edition.
Pain was measured with a single-item self-rating of current pain on a Likert scale of 1–10, from minimal to severe.