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. Author manuscript; available in PMC: 2011 Dec 1.
Published in final edited form as: Transl Res. 2010 Dec;156(6):335–349. doi: 10.1016/j.trsl.2010.09.003

Figure 1. A) Fraction of Exhaled Nitric Oxide (FeNO), B) Whole Lung Homogenate Nitrate/Nitrite Levels.

Figure 1

A). The effect of simvastatin on in vivo FeNO measurements as described in Methods. Simvastatin (40 mg/kg) treatment decreased FeNO by 61.7% (*p<0.0019 by Kruskal-Wallis test) down to air control levels. Simvastatin and MA (20 mg/kg) co-treatment did not reverse the inhibitory statin effect (p=NS, Kruskal-Wallis test). Each treatment group had between 5–8 mice.

B) Treatment with simvastatin did not alter whole lung nitrate/nitrite content, an indicator of NO production (p=NS by 1-way ANOVA). Each treatment group had between 6–9 mice.