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Values of binding affinities and number of binding sites on apotransferrin calculated by ITC for all five Ru(II) complexes and the controls: chloroquine diphosphate (CQDP) and [Ru(η6-p-cymene)(en)Cl][PF6].
| Compound | Binding affinity (M−1) | Binding sites |
|---|---|---|
| CQDP | No binding | No binding |
| Complex 1 | 2.27×104 | 7 |
| Complex 2 | 1.18×105 | 6 |
| Complex 3 | 2.35×104 | 9 |
| Complex 4 | No binding | No binding |
| Complex 5 | 1.77×103 | 11–12 |
| Complex 6 | No binding | No binding |
