Table 1.
Baseline demographic characteristics of patients enrolled in the GENISOS cohort
| Characteristic | Baseline value |
|---|---|
| Age (years) | 48.63 (± 13.5) |
| Ethnicity | |
| White | 125 (46.99%) |
| Hispanic | 77 (28.95%) |
| African American | 54 (20.3%) |
| Other | 10 (3.76%) |
| Female sex | 221 (83.08%) |
| Current smoker | 49 (18.42%) |
| Ever smoker | 134 (50.38%) |
| Disease duration (years)a | 2.53 (± 1.63) |
| Limited skin involvement | 110 (41.35%) |
| Autoantibodies | |
| Antinuclear antibodies | 254 (95.49%) |
| Anti-centromere antibodies | 32 (12.03%) |
| Anti-topoisomerase antibodies | 49 (18.42%) |
| Anti-RNA polymerase III | 61 (22.93%) |
| Anti-U1-ribonucleoprotein | 30 (11.28%) |
| Anti-Ro | 10 (3.8%) |
| Anti-fibrillarin | 28 (10.69%) |
| Percentage predicted forced vital capacity | |
| > 80% | 132 (58.15%) |
| 50 to 80% | 81 (35.68%) |
| < 50% | 14 (6.17%) |
Data presented as mean (± standard deviation) or n (%). aTime interval between date of onset of first non-Raynaud's phenomenon symptom and enrollment.