Table 2.
Age and Multivariate-adjusted OR1 and 95% CI associations between breast cancer and alcohol consumption, CAMA.
| Cases | Controls | Model 1 | Model 2 | |||
|---|---|---|---|---|---|---|
| n (%) | n (%) | OR | 95% CI | OR | 95% CI | |
| Recent Alcohol Intake 2 | ||||||
| Current Drinker | ||||||
| No | 674 (71%) | 818 (79%) | 1.00 | |||
| Yes | 269 (29%) | 222 (21%) | 1.31 | 1.05–1.62 | 0.98 | 0.76–1.27 |
| Alcohol Use, categorical 3 | ||||||
| Non-drinker | 660 (66%) | 819 (76%) | 1.00 | |||
| >0–2 g/day | 188 (19%) | 161 (15%) | 1.42 | 1.11–1.81 | 1.19 | 0.90–1.58 |
| ≥2 g/day | 152 (15%) | 94 (9%) | 1.90 | 1.42–2.53 | 1.20 | 0.85–1.70 |
| Lifetime Alcohol Use4 | ||||||
| Ever drank alcohol | ||||||
| No | 402 (43%) | 567 (55%) | 1.00 | |||
| Yes | 542 (57%) | 473 (45%) | 1.53 | 1.27–1.86 | 1.25 | 0.99–1.58 |
| Ever drink >1 drink per month for ≥ 1 year | ||||||
| No | 768 (81%) | 928 (89%) | 1.00 | |||
| Yes | 176 (19%) | 112 (11%) | 1.91 | 1.47–2.48 | 1.74 | 1.27–2.39 |
| Age (yr) at first alcohol use | ||||||
| Nondrinker | 402 (44%) | 567 (56%) | 1.00 | 1.00 | ||
| >=26 | 132 (14%) | 133 (13%) | 1.37 | 1.00–1.82 | 1.22 | 0.88–1.70 |
| 21–25 | 126 (14%) | 104 (10%) | 1.59 | 1.18–2.15 | 1.24 | 0.86–1.77 |
| 18–20 | 169 (18%) | 124 (12%) | 1.84 | 1.18–2.15 | 1.41 | 1.02–1.96 |
| <18 | 90 (10%) | 90 (9%) | 1.29 | 0.93–1.81 | 0.92 | 0.61–1.39 |
| Age (yr) at first alcohol use, among drinkers | ||||||
| >=26 | 132 (14%) | 133 (13%) | 1.00 | 1.00 | ||
| 21–25 | 126 (14%) | 104 (10%) | 1.00 | 0.66–1.51 | 0.87 | 0.56–1.35 |
| 18–20 | 169 (18%) | 124 (12%) | 1.36 | 0.90–2.06 | 1.04 | 0.69–1.58 |
| <18 | 90 (10%) | 90 (9%) | 1.43 | 0.97–2.10 | 0.71 | 0.44–1.15 |
Estimated from conditional logistic regression models using data from 1000 cases and 1074 controls (58.5% and 55.7% postmenopausal women, respectively): Model 1 Matching factors only (age, region, and health care institution); Model 2: Model 1+ BMI, family history of breast cancer, age at first pregnancy, number of births, lactation, energy intake, physical activity, education, age at menarche, menopausal status, OC (ever/never),smoking (ever/never), fibrocystic disease, hormone therapy
Recent alcohol (within past year) assessed by Food Frequency Questionnaire
P for trend Model 1 <0.0001; Model 2 =0.19
Lifetime alcohol use assessed using a health questionnaire