Figure 2.

Hippocampus–prefrontal theta coherence at decision points in the rodent during a spatial–reward association task. (A) Inter-areal theta coherence emerges before the junction of the Y-maze. (B) The strength of theta coherence at the decision points goes along with accuracy to choose the correct direction to receive reward. (C) Proportion of theta modulated cell pairs with significant spiketrain correlations (y-axis) before and after learning the task. Red/Blue bars denote correlations for high/low theta coherence periods. (D) Cross-correlation of inhibitory and excitatory neurons show more effective inhibition (at short time lags, x-axis) during periods of high versus low theta coherence (bottom/top panels). (E) During theta rhythmic coherence (top panel), spike timing of pyramidal cells (bottom panel) phase aligned. Adapted with permission from Benchenane et al. (2010).