Fig. 2.

Effects of 10 μM zerumbone (ZER), 20 μM auraptene (AUR), 50 μM nobiletin (NOB), and 20 μM (±)-13-hydroxy-10-oxo-trans-11-octadecenoic acid (13-HOA) against the actions of 1 μM p,p′-DDT or 10 nM TCDD for 24 h in a U937 macrophage model for a CYP1A1, b COX-2, c TNF-α, d MMP-3, and e VEGF mRNAs. mRNAs for selected genes were compared using qRT-PCR approaches and normalized against β-actin. *Treatment significantly different from controls P < 0.05. a Treatment significantly different from TCDD or DDT treatment alone P < 0.05