FIG. 1.

Construct appearance at culture days 21 and 45. Representative constructs cultured in (A, B, E, F, I, J, K) chondrogenic and (C, D, G, H, L, M) osteogenic medium shown in (A–D) macroscopic photos and (E–M) histological sections. The arrow in (F) shows how the woven poly(ɛ-caprolactone) scaffold has been forced apart (arrow) by new tissue growth in this histological cross section. Arrows in (I, J, K) show chondrocytic morphology, whereas arrows in (L, M) show fibroblastic morphology. Stain: hematoxylin and eosin. Scale bars: (A–D) 5 mm, (E–H) 1 mm, and (I–M) 50 μm. Color images available online at www.liebertonline.com/ten.