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. 2010 Nov 24;6(11):e1001012. doi: 10.1371/journal.pcbi.1001012

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This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration, which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

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(a) Predicted temporal variation of the CD4 count during ENF interruption (red) and with ENF re-administration (green). Parameters used are the average values in Tables 1 and 3. The vertical dashed line indicates the time of ENF re-administration. (b) Bar diagram showing the percentage change of CD4 count at the end of one year without ENF (red) and at the end of 3 months with ENF re-administration (green). (c) Change over time of the proportion of uninfected cells, T (blue), cells infected with drug-sensitive virus, I_s (green), and cells infected with drug-resistant virus, I_r (red). The vertical dashed line indicates the time of ENF re-administration.