Figure 5. Discordance Associated Mutations (DAMs) within HIV-1PR alters the generation of TUNEL positivity.

YFP HIV protease or the indicated protease point mutants were expressed in HeLa cells, and the YFP positive cells were analyzed for TUNEL positivity (A, B). *Indicates p value ≤0.05. Data reflective of at least three independent replicates. Bars with solid color represent controls, bars with angled hatching represent DAMs, and bars with horizontal hatching represent non-DAMs.