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. 2010 Nov 24;6(11):e1001205. doi: 10.1371/journal.ppat.1001205

Figure 1. Tick histamine release factor (tHRF) was up-regulated in B. burgdorferi- infected ticks.

Figure 1

(A) The expression of tHRF in B. burgdorferi-infected or uninfected ticks during I. scapularis feeding. Results are expressed as the mean ± the SEM (*p<0.05; **p<0.01). (B) tHRF-antiserum recognizes recombinant tHRF generated in Escherichia coli (tHRF E.coli) or Drosophila S2 cells (tHRF DES). (C–D) The up-regulation of tHRF protein in B. burgdorferi-infected ticks. (*p<0.05) (E) The detection of tHRF in adult tick saliva (Saliva), nymphal tick salivary glands (S.G.), midgut (M.G.) and whole ticks (Tick).