Table 1.
Type 1 error and power of data sets of simulation 1
| Effect (b) | PCBMR | Single-Trait Association | ||||||
|---|---|---|---|---|---|---|---|---|
| GEN | ADD | DOM | REC | GEN | ADD | DOM | REC | |
| 0 | 5.1 | 4.5 | 5.3 | 5.6 | 5.7(2.8) | 5.8(3.0) | 6.1(2.9) | 4.9(3.0) |
| 0.1 | 5.8 | 5.4 | 6.2 | 4.7 | 5.6(3.1) | 5.8(3.3) | 5.9(3.0) | 5.3(2.8) |
| 0.2 | 10.8* | 12 | 11.2 | 6.8 | 8.9(4.8) | 10.9(6.1) | 10.9(5.7) | 6.4(3.4) |
| 0.3 | 14.1* | 18.8* | 18.3* | 9.1* | 12.2(8.6) | 14.4(9.2) | 14.6(9.6) | 7.3(4.4) |
| 0.4 | 21.4* | 26.8* | 25.2* | 11.3 | 15.9(10.0) | 20.5(14.5) | 19.9(13.1) | 10.4(6.3) |
| 0.5 | 31.9* | 41.9* | 36.7* | 15.7* | 24.3(14.8) | 29.1(20.3) | 27.3(18.1) | 13.6(8.7) |
| 0.6 | 45.4* | 54.9* | 50.1* | 21.3* | 31.6(23.2) | 39.9(30.0) | 36.1(26.7) | 17.2(10.8) |
| 0.7 | 60.3* | 71.4* | 65.0* | 26.5* | 41.9(31.3) | 50.5(40.1) | 47.2(36.9) | 21.6(14.1) |
| 0.8 | 71.9* | 81.9* | 77.3* | 30.9* | 53.3(43.6) | 63.6(51.9) | 58.2(46.9) | 24.2(18.0) |
| 0.9 | 81.7* | 90.8* | 84.3* | 41.7* | 62.5(50.4) | 72.7(62.2) | 66.1(55.6) | 30.4(21.5) |
| 1 | 91.4* | 95.2* | 92.8* | 48.9* | 72.8(62.8) | 82.0(73.4) | 76.7(67.3) | 36.7(27.0) |
(The values outside the parentheses are the power (b > 0) or type I error (b = 0) of the single-trait association test without multiple-test adjustment (SATN) and the values inside the parentheses are the power (b > 0) or type I error (b = 0) of the single-trait association test with Bonferroni adjustment (SATB). * indicates that the power of PCBMR is significantly better than that of SATN; GEN: general model without assumption of genetic inheritance; ADD: additive effect model; DOM: dominant model and REC: recessive model)