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Example of long range variation in mean MHC II affinity across a single protein (Thermonuclease precursor Staphylococcus aureus COL gi 57650135). (A) DRB4*0101 and (B) DRB1*0404 have a high correlation (r = 0.6) while (C) DRB3*0101 and (D) DRB1*0901 have a low correlation.
