. 2010 Nov 5;8:111. doi: 10.1186/1479-5876-8-111

Table 2.

Number of KRECs and TRECs and average number of B-cell divisions

		Patients		Controls

		*median*	IQR*	*median*	*IQR*


KRECs	/10⁶PBMC	200	99-448	5 372	2 798-7 617	P = 0.0001
	/mL	3 763	1 318-6 486	12 942	6 556-19 490	P = 0.0001

Average number		6.7	3.8-14.1	4.0	3.0-4.5	P = 0.003
of B-cell divisions


TRECs	/10⁶PBMC	216	64-949	1 374	834-3 046	P = 0.002
	/mL	2 869	1 601-11 812	3 053	1 960-6 401	NS

KRECs and TRECs were determined by Real-Time PCR. Results are given both as copies/10⁶PBMC and copies/mL. The average number of B-cell divisions was calculated as the difference between the cycle threshold number obtained by PCR amplification of signal joints, and the cycle threshold number obtained after amplification of coding joints.

*Abbreviations: IQR, Interquartile range; KRECs, kappa-deleting recombination excision circles; TRECs, T-cell receptor excision circles.